Abstract: The reaction mechanism of solid-liquid phase transfer catalytic esterification of 2-methylallyl chloride with sodium acetate was investigated. The reaction experiments using 2-methylallyl chloride and sodium acetate as reactants were carried out under different reaction conditions, and the reactant and product concentrations of catalytic esterification by the phase-transfer catalyst of onium salt were obtained for developing mechanism and kinetic equations by sampling at different reaction times. The influence of reaction temperature, stirring speed, type and amount of catalyst, and type of solvent was studied. The results show that the reaction forming 2-methylallyl acetate with catalyst of cetyltrimethylammonium chloride is quasi-first-order reaction and its apparent activation energy of the reaction is 97.61 kJ·mol^-1.