Abstract: Vapor-liquid equilibria (VLE) data for binary systems of 2-methyl-3-butene-2-ol + prenyl alcohol and 3-methyl-3-butene-1-ol + prenyl alcohol were determined at 51.2 kPa and 81.9 kPa respectively in an improved Rose still. All of the VLE data passed the thermodynamic consistency test. Wilson and NRTL models were applied to correlate the VLE data and the interaction parameters were determined. The predicted values were consistent with the experimental data. The maximum absolute deviations of bubble point and vapor phase composition for 2-methyl-3-butene-2-ol + prenyl alcohol system are 0.4 ℃ and 0.002 1, respectively. And those for 3-methyl-3-butene-1-ol + prenyl alcohol system are 0.2 ℃ and 0.0031, respectively. The obtained models can meet the requirement of chemical engineering design and calculation.